I'd sew a piece of muslin to the back of the fabric, outlining the lizard. Trim close to the excess fabric away with a pinking shears. Now cut a slit in the muslin, on the bias if you can, and lightly pad the lizard with some poly batting. Place a patch inside the slit and then turn the edges of the slit inside and hand stitch them down to the patch with tight, close stitches. Alternatively, you can sew a patch over the slit, but the first method is less noticeable.

Annie

I'd sew a stabilizer - you could use a non iron on pellon piece (on the sturdy side). Put it on the back of the lizard you want to stuff, stitch around the lizard leaving a small space to add stuffing, pin and continue stitch until it's closed. Be careful not to over stuff.