| For a fascinating discussion of this subject see the link below. The notion that removal of small primary tumors might *increase* the risk of metastatic cancers is new to me, but it explains a great deal. The Lancet requires free registration. |
Here is a link that might be useful: http://www.thelancet.com/journal/vol358/iss9299/full/llan.358.9299.correspondence.18863.1
