Weight hasn't changed so much, but my energy levels have taken a nosedive. My "back in the day" equivalent is that I used to swear I'd never stop working out consistently. I was fit as a fiddle and proud of my body. I had energy to burn. When I heard older women talk about not being able get themselves to exercise, I thought they lacked willpower. I looked down on their flab. . . . What an ignorant young woman I was. I'm still a good weight, but don't have the tone I used to. The thing is, I know I'd feel a lot better if I was exercising regularly, but my lack of activity seems to have made it even harder to get going. A vicious cycle. I have an appt. next Wed. to meet with my dr. to review my hormone test results. This is for bloodwork -- est, prog, DHEA, thyroid, ferretin (iron). I'm curious to to see what my levels are. Next week I'm also meeting with an allergist for a series of skin tests. Never had food allergies before, but something new I'm dealing with along with perimenopause. I've heard that folks with thyroid problems can have allergies. It's such an issue because I can't tolerate allergy and cold medicines. They just make me feel awful -- something I don't need in addition to hormonal stuff. So, I'm hopingl to find out what foods I need to avoid. I don't care if it's my favorite, I'll drop it like a hot potato. Tina

See if you can get the lab ranges to compare your results to. I did the progesterone test over a period of time and found that it dropped off too soon in my cycle. If they only tested you for one day, it may not tell you a lot, jmho. Don't give up on alternative medicine; there are some good treatments available. My favorite is homeopathy. Good luck! Here is a link that might be useful: Homeopathy

"...kind to offer your flat assurances that you know better than all of us what is best for all of us." In the broadest sense that no drugs is always preferable to drugs when one is discussing drugs that are not necessary to life and limb only, yes. Nowhere in either of your posts in this thread have you even mentioned the grave risks associated with these drugs. You have not mentioned weighing risks vs expected/desired benefits. Instead you suggest that there are (serious and negative) implications that follow from "declining ovarian hormone production." The intact female produces all the estrogen and testosteone required for the non-reproductive body. Progesterone, as the hormone of pregnancy, is not produced because it is no longer required unless one takes exogenous estrogen in which case it is used to counter the extreme carcinogenicity of estrogen. I have my feet sufficiently grounded in reality to know that most women are being pressured to take hormones of some kind after menopause despite the lack of evidence for benefit. They are not warned of the dangers and those who get their drugs from "compounding pharmacies" may well never even see the federally mandated warning that is supposed to be included in all estrogen drug prescriptions. Many women see the word "natural" and assume therefore safe. Compounding pharmacists/pharmacies encourage this belief because it contributes to their bottom line. In this last post you pay lip service to the notion that "absolute minimum" dose is best, but carefully avoid saying that for most women that minimum is none at all. The difference between our approaches is that I make my biases clear upfront. You disguise yours in apparently neutral but actually highly biased language - launguage that is eerily similar to that used by drug companies/compounding pharmacies/mlm scammers and the like to sell their product(s). I wonder if you would post in equally (apparently) neutral fashion, if someone came here asking about the use of street drugs or tobacco.

60mg of what? Three times a day seems like an unusual dose for any Cushings meds. Huge dog? Lysodren, also known as OPDDD or mitotane, is a medication that targets the adrenal gland and is actually toxic for it, slowly killing certain portions of it. If the balance is right, the idea is to kill the cells producing too much cortisone slowly, but not to wipe out then entire adrenal gland (resulting in a somewhat 'opposite' condition known as Addisons). It is a pretty effective drug, and is usually given far less often (not daily long term) than Trilostane is, but should be taken carefully and with close monitoring. However, for huge dogs, it can pretty costly, too, perhaps even more than Trilostane. TRilostane can be compounded and sometimes the compounded forms (depending on which pharmacy one chooses) can be far less costly than Vetaryl (the drug name for this product in the US).