I assume this is Dupont Teflon and it doesnt change the feel of the fabric. The molecules and penetration is at a microfiber level. Natural fibers benefit more from this than synthetic fibers.

I would also say that most fabric treatments are designed to make the cleaning easier, not to "prevent stains." Unless that's what you mean by preventing stains, making the stain cleanable.

The principle is that they prevent stains bonding to fibers. There may be added advantage that water-based stains bead up on certain fabrics (surface tension), allowing you to blot up the liquid.

This will help with saliva, urine, or beverages but this may not do much for dog's body oils rubbing against the edges, for example.

Thank you both for your comments.