As I have said I still have a flea problem altho all five cats were Frontlined a month ago as well as the dog, and he's on Sentinel as well. I called the place where I got the product and told them I applied it July 7 and still have fleas on all animals. She told me they stand by their product and if with this dose I see no improvement, they will send more. Dog was a piece of cake and three of the cats were. One is hiding but she will be easy, but Henry went ballistic again, much worse than the last time.. This is insane. I have had 15 cats over the years and have treated most of them with Frontline with no problem. They don't line up for it but most are okay, some struggle a little but Henry is a mad man. I hope it reached it's target. I had him on the island and he was lovey. I was combing him and he loves that. Husband quietly appeared with the allready opened package, and it took two of us struggling like mad to control a 21 pound cat. There was hair everywhere , and he was screaming.. A passerby would have thought we were torturing him. Other than knocking him over the head w/ a hammer(just kidding) , what can I do? I have never seen a wilder animal in my life. I rescued him at 4 weeks from his semi feral mother but he's a big love most of the time. A in your face and on your lap cat.