what the doctor forgot to tell me
On December 25, 1996, Dr. Larry Clark and his colleagues published their large, prospective, randomized, placebo-controlled, double-blind Nutritional Prevention of Cancer (NPC) clinical study in the Journal of the American Medical Association (JAMA 1996; 276:1957-1963). This landmark research effort showed that daily supplementation of diets with 200 micrograms of selenium yeast cut the cancer death rate in half. That is cancer mortality was reduced 50 percent (p=0.002). Lung cancer deaths were reduced 53% (p=0.03)
Total cancer incidence was reduced 37 percent (p=0.001) and the total carcinoma incidence was reduced 45%. In addition, the three leading sites of cancer had significantly lower incidence; lung cancer incidence was reduced 46 percent (p=0.04), prostate cancer incidence was reduced 63 percent (p=0.002) and colon cancer incidence was reduced 58 percent (p=0.03). There was a 17% reduction in all cause mortality (p=0.14), which when adjusted for sex, current smoking and age yielded a 21% reduction in deaths from all causes (p=0.07).